According to the Associated Press, a large-scale study funded by the National Institute of Allergy and Infectious Diseases at the Infectious Diseases Conference in Washington on the 26th showed that AIDS patients should receive medication earlier, rather than before. Do not start taking the drug until the immune system is severely damaged.
The results of this study will likely change the fate of countless AIDS patients.
According to the current guidance of the US government and the International AIDS Society, patients should not take medication until the symptoms of AIDS appear, that is, before the number of T cells per cubic millimeter in the blood drops to 350 (the number of T cells in normal people should exceed 800). Because the medical community generally believes that although the combination drug therapy used since the mid-1990s is effective, it can cause heart problems, high cholesterol, and side effects such as dysentery and nausea. The drug may be more harmful to the body than the disease itself, and resistant. The medicinal properties will also reduce the efficacy of the drug. Therefore, taking medication as late as possible can reduce the harm of side effects to the human body.
However, the results of the research published at the Infectious Diseases Conference held in Washington on the 26th gave different opinions. The researchers believe that it is necessary to start AIDS as soon as possible and start drug treatment as soon as possible, which will effectively extend the lives of patients.
Between 1996 and 2006, under the leadership of Dr. Marty Gita Hatta of the University of Washington in Seattle, researchers tracked 8,374 AIDS patients between 351 and 500 in the United States and Canada. Thirty percent of the patients took the drug from the beginning, and the other patients followed the instructions and waited until the T cell count dropped below 350 to receive medication.
"We found that 70% of patients with T cells between 351 and 500 received better medication than those who did not," said Dr. Gita Hatta.
Dr. Robert Scully, director of the Infectious Diseases Research Program at the University of California, San Diego, said, "All studies have shown that our treatment started too late. It is necessary to start with medication." Scully The Ph.D. has assisted the AIDS Society in preparing guidance and advising a number of companies producing anti-AIDS drugs.
Dr. Anthony Foz, director of the National Institute of Allergy and Infectious Diseases, said that the improvement of drug therapy and new research results will further push doctors to re-examine this guidance. He expects doctors to get their patients to receive medication earlier before the guidelines are revised. Moreover, in recent years, the side effects of new combination drug therapies have become smaller and smaller. Some therapies only need to take one or two pills a day, and long-term adherence is no longer a problem.
But the bigger problem is that one-third of people living with HIV (HIV) are diagnosed with AIDS too late, when their T-cell count has dropped below 350 or they already have serious complications.
â€œPeople are still too late to find HIV,â€ said Dr. Daniel Kurizko, an AIDS specialist at the Boston Women's Hospital in Boston. â€œThe new research results further demonstrate the importance of early diagnosis of HIV infection.â€
According to reports, about 56,300 Americans are infected with HIV each year, which destroys T cells that help immune cells fight bacterial invasion. Once the T cells are broken, the patient falls into a series of deadly diseases.
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